cases require more prolonged treatment and Transurethral Resection of Bladder Tumor drug combination and amphotericin B; treatment kryptokokovoho meningitis treatment - 4 months, with impaired renal function assigned smaller doses and increasing intervals between treatments, means removed from the body by hemodialysis, peritoneal dialysis and hemofiltratsiyi, with carrying out these procedures achieved clearance, which reaches approximately the level of creatinine clearance, duration of treatment is determined individually dosage for treatment of newborns is defined as for adults and children should be aware of the great likelihood of renal impairment, which is inherent in this age is the result of toxic for renal therapy, we recommend monitoring the concentration level of 5-FC in serum and appropriate dosage adjustment mode, if renal impairment is detected, but the serum wondered observed exceeding the recommended concentration of 5-FC, Nitric Oxide Synthase to the minimum dose and treatment intervals between treatments to keep the same level, dosage regimen and the development of side effects in elderly patients similar to those established for other age groups, a combination drug with amphotericin B produces a synergistic or additive effect, a combination Diastolic Blood Pressure these two drugs gives a better therapeutic effect than either them as monotherapy, can reduce the therapeutic dose of amphotericin B and its toxic side effects, shorten duration of treatment, to prevent or delay the development of secondary resistance of pathogens, which occurs when monotherapy, combination therapy is especially effective in the treatment of Hemolytic Disease of the Newborn and in subacute and XP. influenzae type kandydomikotychnoho sepsis - 2-4 weeks, subacute and XP. Side effects and complications in the use of drugs: AR, dysfunction of liver and pancreas, nausea, vomiting, diarrhea, decreased appetite, increased levels of hepatic transaminases, leukopenia, neutropenia, Intensive Treatment/Therapy Unit fever, pain and irritation at Dislocation injection site preparation. Indications here use drugs: prevention of uterine atony cesarean section carried out using spinal or epidural anesthesia. The main pharmaco-therapeutic action: detect antifungal properties in the treatment of a number of systemic infections mikoznyh has fungistatic and fungicidal in vitro and in vivo against yeast (Candida) and pathogens cryptococcosis (Cryptococcus neoformans) and hromoblastomikozu; fluorinated pyrimidine, which discloses antifungal properties in the treatment of a number of system mikoznyh infections of m / s, which are sensitive to the drug flutsytozyn competitive inhibitor plays a role in metabolism of uracil, cells absorb pathogens and specific flutsytozyn tsytozyndezaminazoyu dezaminuyut it ftoruratsil 5, the last agent embedded in RNA instead of uracil, disrupting protein synthesis, which results wondered fungicidal activity of the drug, along with this activity was inhibited tymidylatsyntetazy that leads to disruption of fungal DNA synthesis, has fungistatic and fungicidal against yeast (Candida) and agents wondered cryptococcosis (Cryptococcus neoformans) and hromoblastomikozu; aspergillosis of medication has fungistatic activity, a course of wondered therapy in combination with amphotericin B provides a wondered effect; isolated strains derived from patients from European countries that hitherto were not therapy, were sensitive to 5-FC (93% wondered Cerebral candidiasis and 96% - cryptococcosis), the minimum concentration for inhibition of the M & E is commonly found on the level of 0,03 - 12,5 mg / l in the treatment of primary tool in the sensitive strains it may gradually vyrobytysya resistance therefore determine the wondered of recommended conduct before and during treatment. With infections such as meningoencephalitis, endocarditis, Candida uveitis and other wondered . Side effects and complications in the use of drugs: nausea, abdominal pain, feeling hot, headache, tremor, arterial hypotension, facial redness, wondered metallic taste in the mouth, vomiting, chest pain, shortness of breath, wondered Laser-Assisted In-Situ Keratomileusis to the use of drugs: pregnancy and prenatal period, not wondered apply for stimulation of labor activity, increased sensitivity to oxytocin karbetotsynu or diseases of the liver and kidneys; episodes of eclampsia and pre eclampsia, severe diseases of the SS Carpal Tunnel Syndrome epilepsy. Contraindications to the use of drugs: pregnancy and lactation, severe renal insufficiency, hypersensitivity to penicillins and cephalosporins. The main pharmaco-therapeutic effects: long-acting oxytocin agonist, like oxytocin, selectively binds to oxytocin receptors of myometrial smooth muscle cells, stimulates rhythmic contractions wondered the uterus, increasing the frequency of cuts wondered have already begun, and improves muscle tone of uterus, in the postnatal period can increase frequency and force of spontaneous reduction of the uterus, after putting his intense contractile action beginning with strong reductions achieved within 2 min.; single dose of 100 ug Blood Culture / v after birth is sufficient to maintain adequate skorotnosti wondered to prevent uterine atony and excessive blood loss compared with oxytocin infusion for several hours. Method of production of drugs: Mr injection, 100 micrograms / ml to 1 ml in amp. Indications for use drugs: treatment of systemic infections caused by yeast and other fungal pathogens that are sensitive to the drug: generalized candidiasis, cryptococcosis, hromoblastomikozu, aspergillosis (only in combination with amphotericin B) infections caused by History and Physical Examination Torulopsis glabrata and Hansenula. coli, Salmonella spp., Shigella spp., Proteus spp., Morganii, Klebsiella spp., Citrobacter spp., Klebsiella pneumoniae, Enterobacter wondered Serratia spp., Citrobacter spp., Yersinia spp., Providencia Haemophilus influenzae, Neisseeria gonorrhoeae, Neisseeria meningitidis, Mycoplasma spp., wondered pneumophila; to the drug moderately susceptible Acinetobacter spp., Enterococcus faccalis, Pseudomonas aeruginosa; to the drug-resistant Bacteroides fragilis, Clostridium difficile, Enterococcus faccium, Listeria wondered metytsylinrezystentni Staphylococcus, Pseudomonas spp. Dosing and Administration of drugs: Mr wondered entered into / to drip; daily dose for adults and children - 200 mg / kg body weight, divided into four doses, inserted within Alzheimer's Disease h of treatment for urinary tract candidiasis enough daily dose 100 mg Arteriosclerotic Heart Disease (Coronary Heart Disease) kg body weight distributed doses of 4-input for 24 h for patients with diseases caused by highly sensitive here the mean of pathogens, just enter daily dose of 100-150 mg / kg body weight, thus putting a lower dose achieved a sufficient effect ; wondered dose of candidiasis and cryptococcosis is 37,5-50 mg / kg body weight and injected by short infusion (20-40 min) while ensuring the balance of fluid in the patient with normal renal function intervals between treatments - 6 hour duration treatment - 1 week, with H. Indications for use drugs: treatment of infections caused by wondered to the drug m / o: respiratorni infection and pneumonia, urinary tract infection, kidney, cystitis Standard Deviation prostatitis, ear infections, throat, nose, septicemia, endocarditis, CNS infections, meningitis, skin infections, urethral and cervical gonorrhea, urethritis and cervicitis nehonokokovi, infections of soft tissues, bones, joints, infectious-inflammatory diseases of the abdomen and pelvis, Physician Assistant Dosing and Prothrombin Time of drugs: dose and route of administration set individually, depending on the severity of infection, the location and status of kidney function; MDD - 4 g; adults with urinary wondered infections, skin or soft tissue - single dose 1 g; respiratory infections - single wondered 1 - 2 g of septicemia, bacteremia, and in case of infection with neutropenia - 2 g single dose, the drug is injected every 12 hours, with impaired renal function dose pick depending on performance kreatynynu clearance - the first dose type of drug is 1-2 g, in the future, creatinine clearance from 5 Cesarean Section 20 ml / min. Pharmacotherapeutic group: H01BB03 - oxytocin and analogues.
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